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KMID : 0604520050310010035
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Journal of the Society of Cosmetic Scientists of Korea
2005 Volume.31 No. 1 p.35 ~ p.41
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Anti-irritation and Moisturizing Effects of Exopolysaccharide Produced by Grifola frondosa
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Lee Beom-Cheon
Kim Jin-Hwa
Bae Joon-Tae
Lee Dong-Hwan
Sim Gwan-Sub
Pyo Hyeong-Bae
Choe Tae-Boo
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Abstract
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We investigated the effects of skin hydration and anti-irritation of exopolysaceharide (GF-glucan) produced from submerged culture of Grifola frondosa. The moisturizing effects and trans-epidermal water loss (TEWL) of GF-glucan in cosmetic products (O/W emulsion) were clinically studied. GF-glucan showed good skin hydration effects when compared with sodium hyaluronate which is a commonly using moisturizer. The skin protective effects of GF-glucan against sodium lauryl sulfate (SLS) were also found. Twice a day application of the CF-glucan to skin reduced local inflammation remarkably. Irritant reactions were assessed by various aspects of skin function, erythema (skin color reflectance), hydration (electrical capacitance) and TEWL. In the human skin test, 5-day treatment of the GF-glucan was found to reduce SLS-induced skin erythema and Improve bier regeneration. Taken all together, GF-glucan should be a very useful cosmetic ingredient, as a moisturizer, and a protecting agent for various skin irritations.
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KEYWORD
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Grifola frondosa, exopolysaceharide, skin protection, anti-inflammation, moisturizer
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